SOMNOTOL

The following is a dosage chart for IP injection of Somnotol [65 mg/ml] in rats. The dosage for females is 35 mg/kg. The dosage for males is 50 mg/kg. Some researchers routinely administer higher doses to induce anaesthesia (50 & 65 mg/kg for females and males respectively).

 

Weight

Female

Male

150

.08

.12

160

.09

.12

170

.09

.13

180

.10

.14

190

.10

.15

200

.11

.16

210

.11

.16

220

.12

.17

230

.12

.18

240

.13

.18

250

.13

.19

260

.14

.20

270

.15

.21

280

.15

.22

290

.16

.22

300

.16

.23

310

.17

.24

320

.17

.25

330

.18

.25

340

.18

.26

350

.19

.27

360

.19

.28

370

.20

.28

380

.20

.29

390

.21

.30

400

.22

.31

Somnotol is a suitable anaesthetic for procedures which can be completed in approximately 1 hour. Supplemental injections of 1/4 the induction dose may be administered, but the risk of overdose rises sharply.

Steve Milway

Last modified: Friday, December 19, 2003